Review and Progress

The Interaction between Aedes aegypti Gut Microbiota and Dengue Fever Virus  

Yulin Zhou
Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China
Author    Correspondence author
Journal of Mosquito Research, 2024, Vol. 14, No. 1   doi: 10.5376/jmr.2024.14.0001
Received: 01 Nov., 2023    Accepted: 10 Dec., 2023    Published: 01 Jan., 2024
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Zhou Y.L., 2024, The The interaction between Aedes aegypti gut microbiota and dengue fever virus, Journal of Mosquito Research, 14(1): 1-9 (doi: 10.5376/jmr.2024.14.0001)


This study aims to explore the mutual influence between the gut microbiota of Aedes aegypti mosquitoes and dengue fever virus. Through the analysis of microbial communities in Aedes aegypti mosquito populations from different geographical regions, significant differences in microbial composition were observed. Further research indicates a certain correlation between microbial diversity and the level of dengue fever virus infection in mosquitoes, suggesting a potentially crucial role of the microbiota in host immune regulation. Experimental evidence reveals that some microbes may positively impact inhibiting the transmission of the dengue fever virus by activating the mosquito's immune system and producing antiviral substances. The final results demonstrate a significant influence of the microbiota on the efficiency of dengue fever virus transmission. This study deepens our understanding of the interplay between Aedes aegypti and the dengue fever virus, providing new research directions for future vector control.

Aedes aegypti mosquitoes; Interaction; Microbial community; Dengue fever virus; Vector control
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