Review and Progress

The Impact of Releasing Aedes aegypti Mosquitoes Edited by CRISPR in The Wild on Local Ecosystems  

Yulin Zhou , Jinni Wu
Cuixi Biotechnology Research Institute, Zhuji, 311800, China
Author    Correspondence author
Journal of Mosquito Research, 2024, Vol. 14, No. 1   doi: 10.5376/jmr.2024.14.0002
Received: 15 Dec., 2023    Accepted: 22 Dec., 2023    Published: 03 Jan., 2024
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Wu J.N., Zhou Y.L., 2024, The impact of releasing Aedes aegypti mosquitoes edited by CRISPR in the wild on local ecosystems, Journal of Mosquito Research, 14(1): 1-8 (doi: 10.5376/jmr.2024.14.0002)


The aim of this study was to investigate the potential impacts of releasing CRISPR-edited Aedes aegypti mosquitoes in the wild on local ecosystems. Aedes aegypti mosquitoes, as an important vector mosquito species, play a pivotal role in the transmission of infectious diseases such as yellow fever and dengue fever. With the rise of CRISPR editing technology, there is an opportunity to reduce the potential of mosquitoes to transmit diseases by precisely editing their genes. The release of this technology in the wild could trigger a range of ecological issues, including ecological niche changes, impacts on food chains and ecological balance, and possible alterations to the adaptive and competitive relationships of non-target species. By exploring these potential impacts in depth, this study aims to provide a comprehensive understanding of the ecological risks and opportunities of CRISPR editing technology in Aedes aegypti mosquitoes, and to provide a reference for its rational and prudent field application.

Aedes aegypti mosquitoes; CRISPR editing technology; Ecosystem impacts; Ecological balance; Vector control
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