Review and Progress

The Chemical Composition and Attack Mechanism of the Venom of Holometabolous Insects  

Tianxia Guo
Institute of Life Science, Jiyang College of Zhejiang A&F University, Zhuji, 311800, China
Author    Correspondence author
Molecular Entomology, 2023, Vol. 14, No. 5   doi: 10.5376/me.2023.14.0005
Received: 07 Aug., 2023    Accepted: 14 Aug., 2023    Published: 29 Aug., 2023
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Guo T.X., 2023, The chemical composition and attack mechanism of the venom of holometabolous insects, Molecular Entomology, 14(5): 1-7 (doi: 10.5376/me.2023.14.0005)


Holometabolous insects are a very special type of insect, and their venom has unique components and strong attacking ability. In this paper, the venom of various holometabolous insects was extracted and separated, and the main chemical components of the venom were identified using various analytical methods. At the same time, this paper also explored the action mechanism, targets, and pathways of venom components. The research results showed that the chemical components of venom in holometabolous insects had various biological activities, including antibacterial, anti-tumor, analgesic effects, etc. In addition, venom could also affect the physiology and behavior of hosts, such as inducing itching, paralysis, and other symptoms. Finally, this paper discussed the potential of venom in medical and agricultural applications.

Holometabolous insects; Venom; Chemical composition; Attack mechanism; Biological activity
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